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Human NSUN6 Recombinant Protein (N-His)
Key Features

Human NSUN6 Recombinant Protein (N-His) (GXRP10849)

SKU GXRP10849
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human NSUN6 Recombinant Protein (N-His)

Human NSUN6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Thr469, with an N-terminal His tag. Predicted molecular weight: 53.93 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 is a ~51 kDa protein. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr)(TGT) and tRNA(Cys)(GCA). For research use only.

In vitro also methylates tRNA(Thr)(AGT). Methylation requires, in the acceptor stem region, the presence of the 3'-CCA terminus, the target site C72, the discriminator base U73, and the second and third base pairs (2:71 and 3:70) in the tRNA substrates.

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