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Human NUAK2 Recombinant Protein (N-His)
Key Features

Human NUAK2 Recombinant Protein (N-His) (GXRP09791)

SKU GXRP09791
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human NUAK2 Recombinant Protein (N-His)

Human NUAK2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys46-Gly306, with an N-terminal His tag. Predicted molecular weight: 32.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. NUAK family SNF1-like kinase 2 is a ~69 kDa protein. Stress-activated kinase involved in tolerance to glucose starvation. For research use only.

Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Phosphorylates LATS1 and LATS2.

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