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Human P2RX6 Recombinant Protein (N-His)
Key Features

Human P2RX6 Recombinant Protein (N-His) (GXRP05120)

SKU GXRP05120
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human P2RX6 Recombinant Protein (N-His)

Human P2RX6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys61-Gly333, with an N-terminal His tag. Predicted molecular weight: 33.02 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. P2X purinoceptor 6 (P2RX6) is a ~48 kDa protein. May act as a modulatory subunit rather than a functional channel. For research use only.

Unlike other P2XRs members, P2RX6 does not seem to form functional homotrimers. P2RX6 requires the presence of P2RX4 or P2RX2 to shuttle it to the plasma membrane where it may form functional heterotrimeric receptors at the plasma membrane. P2RX6 can be translocated to the nucleus and functions as a nuclear regulator of post-transcriptional modifications in neurons.

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