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Human PACS2 Recombinant Protein (N-His)
Key Features

Human PACS2 Recombinant Protein (N-His) (GXRP07657)

SKU GXRP07657
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human PACS2 Recombinant Protein (N-His)

Human PACS2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met22-His181, with an N-terminal His tag. Predicted molecular weight: 20.01 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phosphofurin acidic cluster sorting protein 2 (PACS2) is a ~97 kDa protein. Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. For research use only.

In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

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