Description
Human PAK6 Recombinant Protein (N-His)
Human PAK6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr386-Cys681, with an N-terminal His tag. Predicted molecular weight: 36.04 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Serine/threonine-protein kinase PAK 6 (PAK6) is a ~74 kDa protein. Serine/threonine protein kinase that plays a role in the regulation of gene transcription. For research use only.
The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Also inhibits ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1.
| Product Name: | Human PAK6 Recombinant Protein (N-His) |
| SKU: | GXRP06416 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PAK-6, PAK5, PAK-5, PAK6, p21-activated kinase 6, Serine/threonine-protein kinase PAK 6 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr386-Cys681 |
| Calculated MW: | 36.04 kDa |
| UniProt: | Q9NQU5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
