Description
Human PARP2 Recombinant Protein (N-His)
Human PARP2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser223-Trp583, with an N-terminal His tag. Predicted molecular weight: 43.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Poly [ADP-ribose] polymerase 2 (PARP2) is a ~66 kDa protein. Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. For research use only.
Mediates glutamate, aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. Mediates glutamate and aspartate ADP-ribosylation of target proteins in absence of HPF1. Following interaction with HPF1, catalyzes serine ADP-ribosylation of target proteins; HPF1 conferring serine specificity by completing the PARP2 active site.
| Product Name: | Human PARP2 Recombinant Protein (N-His) |
| SKU: | GXRP03514 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | hPARP-2, PARP-2, ADPRT-2, NAD(+) ADP-ribosyltransferase 2, ADPRTL2, PARP2, ARTD2, Poly[ADP-ribose] synthase 2, Protein poly-ADP-ribosyltransferase PARP2, DNA ADP-ribosyltransferase PARP2, ADPRT2, ADP-ribosyltransferase diphtheria toxin-like 2, Poly [ADP-ribose] polymerase 2, pADPRT-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser223-Trp583 |
| Calculated MW: | 43.19 kDa |
| UniProt: | Q9UGN5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
