Description
Human PAX5 Recombinant Protein (N-His)
Human PAX5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-His391, with an N-terminal His tag. Predicted molecular weight: 44.31 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Paired box protein Pax-5 (PAX5) is a ~42 kDa protein. Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. For research use only.
Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage-specific genes. In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage. Repression of the cohesin-release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire.
| Product Name: | Human PAX5 Recombinant Protein (N-His) |
| SKU: | GXRP02029 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | B-cell-specific transcription factor, Paired box protein Pax-5, BSAP, PAX5 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-His391 |
| Calculated MW: | 44.31 kDa |
| UniProt: | Q02548 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
