Description
Human PCGF6 Recombinant Protein (N-His)
Human PCGF6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp252-Thr350, with an N-terminal His tag. Predicted molecular weight: 13.33 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Polycomb group RING finger protein 6 is a ~39 kDa protein. Transcriptional repressor. For research use only.
May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.
| Product Name: | Human PCGF6 Recombinant Protein (N-His) |
| SKU: | GXRP10811 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MBLR, Mel18 and Bmi1-like RING finger, PCGF6, Polycomb group RING finger protein 6, RING finger protein 134, RNF134 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp252-Thr350 |
| Calculated MW: | 13.33 kDa |
| UniProt: | Q9BYE7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
