Description
Human PCLAF Recombinant Protein (N-His)
Human PCLAF Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Glu111, with an N-terminal His tag. Predicted molecular weight: 14.15 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. PCNA-associated factor (PCLAF) is a ~11 kDa protein. PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. For research use only.
Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
| Product Name: | Human PCLAF Recombinant Protein (N-His) |
| SKU: | GXRP03473 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PAF, Overexpressed in anaplastic thyroid carcinoma 1, PCNA-associated factor of 15 kDa, PCLAF, Hepatitis C virus NS5A-transactivated protein 9, PCNA-associated factor, OEATC-1, PCNA-clamp-associated factor, PAF15, HCV NS5A-transactivated protein 9, p15PAF, NS5ATP9, KIAA0101 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Glu111 |
| Calculated MW: | 14.15 kDa |
| UniProt: | Q15004 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
