Description
Human PDE10A Recombinant Protein (N-His)
Human PDE10A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn508-Asp779, with an N-terminal His tag. Predicted molecular weight: 33.29 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A) is a ~114 kDa protein. Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. For research use only.
Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.
| Product Name: | Human PDE10A Recombinant Protein (N-His) |
| SKU: | GXRP03096 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | cAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10A, PDE10A |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn508-Asp779 |
| Calculated MW: | 33.29 kDa |
| UniProt: | Q9Y233 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
