Description
Human PEX1 Recombinant Protein (N-His)
Human PEX1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala15-Ile177, with an N-terminal His tag. Predicted molecular weight: 20.68 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Peroxisomal ATPase PEX1 is a ~142 kDa protein. Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. For research use only.
Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
| Product Name: | Human PEX1 Recombinant Protein (N-His) |
| SKU: | GXRP12139 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:3.6.4.-, PEX1, Peroxin-1, Peroxisomal ATPase PEX1, Peroxisome biogenesis disorder protein 1, Peroxisome biogenesis factor 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ala15-Ile177 |
| Calculated MW: | 20.68 kDa |
| UniProt: | O43933 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
