Description
Human PKD2 Recombinant Protein (N-His)
Human PKD2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met242-Thr468, with an N-terminal His tag. Predicted molecular weight: 28.28 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Polycystin-2 (PKD2) is a ~109 kDa protein. Forms a nonselective cation channel. For research use only.
Can function as a homotetrameric ion channel or can form heteromer with PKD1. Displays distinct function depending on its subcellular localization and regulation by its binding partners. In primary cilium functions as a cation channel, with a preference for monovalent cations over divalent cations that allows K(+), Na(+) and Ca(2+) influx, with low selectivity for Ca(2+). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium.
| Product Name: | Human PKD2 Recombinant Protein (N-His) |
| SKU: | GXRP04772 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Autosomal dominant polycystic kidney disease type II protein, TRPP2, PC2, Polycystwin, Transient receptor potential cation channel subfamily P member 2, Polycystin-2, PKD2, Polycystic kidney disease 2 protein, R48321 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met242-Thr468 |
| Calculated MW: | 28.28 kDa |
| UniProt: | Q13563 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
