Description
Human PKP2 Recombinant Protein (N-His)
Human PKP2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp571-Ala849, with an N-terminal His tag. Predicted molecular weight: 25.22 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Plakophilin-2 (PKP2) is a ~97 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. For research use only.
Regulates focal adhesion turnover resulting in changes in focal adhesion size, cell adhesion and cell spreading, potentially via transcriptional modulation of beta-integrins. Required to maintain gingival epithelial barrier function. Important component of the desmosome that is also required for localization of desmosome component proteins such as DSC2, DSG2 and JUP to the desmosome cell-cell junction. Required for the formation of desmosome cell junctions in cardiomyocytes, thereby required for the correct formation of the heart, specifically trabeculation and formation of the atria walls.
| Product Name: | Human PKP2 Recombinant Protein (N-His) |
| SKU: | GXRP02789 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PKP2, Plakophilin-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp571-Ala849 |
| Calculated MW: | 25.22 kDa |
| UniProt: | Q99959 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
