Description
Human PLIN5 Recombinant Protein (N-His)
Human PLIN5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn21-Val369, with an N-terminal His tag. Predicted molecular weight: 40.42 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Perilipin-5 is a ~50 kDa protein. Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. For research use only.
Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2.
| Product Name: | Human PLIN5 Recombinant Protein (N-His) |
| SKU: | GXRP10744 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | LSDP5, Lipid storage droplet protein 5, OXPAT, PAT-1, PLIN5, Perilipin-5 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn21-Val369 |
| Calculated MW: | 40.42 kDa |
| UniProt: | Q00G26 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
