Description
Human POLE Recombinant Protein (N-His)
Human POLE Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser30-Lys495, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA polymerase epsilon catalytic subunit A is a ~261 kDa protein. Catalytic component of the DNA polymerase epsilon complex. For research use only.
Participates in chromosomal DNA replication. Required during synthesis of the leading DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork. Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication. Involved in DNA synthesis during DNA repair.
| Product Name: | Human POLE Recombinant Protein (N-His) |
| SKU: | GXRP13755 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 3'-5' exodeoxyribonuclease, DNA polymerase II subunit A, DNA polymerase epsilon catalytic subunit A, EC:2.7.7.7, EC:3.1.11.-, POLE, POLE1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser30-Lys495 |
| UniProt: | Q07864 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
