Description
Human POLG2 Recombinant Protein (N-His)
Human POLG2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg182-Val485, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA polymerase subunit gamma-2 is a ~54 kDa protein. Accessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). For research use only.
Acts as an allosteric regulator of the holoenzyme activities. Enhances the polymerase activity and the processivity of POLG by increasing its interactions with the DNA template. Suppresses POLG exonucleolytic proofreading especially toward homopolymeric templates bearing mismatched termini. Binds to single-stranded DNA.
| Product Name: | Human POLG2 Recombinant Protein (N-His) |
| SKU: | GXRP13062 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | DNA polymerase gamma accessory 55 kDa subunit, DNA polymerase subunit gamma-2, MTPOLB, Mitochondrial DNA polymerase accessory subunit, MtPolB, POLG2, PolG-beta, p55 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg182-Val485 |
| UniProt: | Q9UHN1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
