Description
Human PPID Recombinant Protein (N-His)
Human PPID Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln7-Pro206, with an N-terminal His tag. Predicted molecular weight: 24.03 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Peptidyl-prolyl cis-trans isomerase D (PPID) is a ~40 kDa protein. PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. For research use only.
Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus.
| Product Name: | Human PPID Recombinant Protein (N-His) |
| SKU: | GXRP02110 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Rotamase D, 40 kDa peptidyl-prolyl cis-trans isomerase, PPID, Cyclophilin-40, Peptidyl-prolyl cis-trans isomerase D, PPIase D, CYP40, CYP-40, Cyclophilin-related protein, CYPD |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln7-Pro206 |
| Calculated MW: | 24.03 kDa |
| UniProt: | Q08752 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
