Description
Human PPP6C Recombinant Protein (N-His)
Human PPP6C Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu305, with an N-terminal His tag. Predicted molecular weight: 37.31 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) is a ~35 kDa protein. Catalytic subunit of protein phosphatase 6 (PP6). For research use only.
PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Down-regulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
| Product Name: | Human PPP6C Recombinant Protein (N-His) |
| SKU: | GXRP07296 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, 3.1.3.16, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu305 |
| Calculated MW: | 37.31 kDa |
| UniProt: | O00743 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
