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Human PRKX Recombinant Protein (N-His)
Key Features

Human PRKX Recombinant Protein (N-His) (GXRP11045)

SKU GXRP11045
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human PRKX Recombinant Protein (N-His)

Human PRKX Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser45-Arg301, with an N-terminal His tag. Predicted molecular weight: 32.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. cAMP-dependent protein kinase catalytic subunit PRKX is a ~40 kDa protein. Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. For research use only.

Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.

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