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Human Protein Disulfide Isomerase A2 / PDIA2 ELISA Kit

SKU:
HUFI02718
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q13087
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
PDIA2
Reactivity:
Human
Research Area:
Cell Biology
€599
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Description

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Human Protein Disulfide Isomerase A2 / PDIA2 ELISA Kit

PDIA2 (Protein Disulfide Isomerase Family A Member 2) encoded protein is a member of the protein disulfide isomerase family. This protein catalyzes the rearrangement of disulfide bonds in proteins, and is required for the correct folding of proteins. Mutations in the PDIA2 gene can result in disorders of protein folding, including cystic fibrosis and α1-antitrypsin deficiency. Patients with cystic fibrosis also have thick mucus that builds up in their lungs, which can cause pneumonia. α1-antitrypsin deficiency is a genetic disorder that affects the liver. PDIA2 has also been implicated in aging.