Description
Human PTPN1 Recombinant Protein (N-His)
Human PTPN1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asn321, with an N-terminal His tag. Predicted molecular weight: 39.47 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) is a ~49 kDa protein. Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. For research use only.
Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
| Product Name: | Human PTPN1 Recombinant Protein (N-His) |
| SKU: | GXRP01088 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | PTPN1, PTP-1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP1B |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asn321 |
| Calculated MW: | 39.47 kDa |
| UniProt: | P18031 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
