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Human PTPRN2 Recombinant Protein (N-His)
Key Features

Human PTPRN2 Recombinant Protein (N-His) (GXRP02674)

SKU GXRP02674
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human PTPRN2 Recombinant Protein (N-His)

Human PTPRN2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys839-Gln1015, with an N-terminal His tag. Predicted molecular weight: 22.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) is a ~111 kDa protein. Plays a role in vesicle-mediated secretory processes. For research use only.

Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain.

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