Description
Human PTPRS Recombinant Protein (N-His)
Human PTPRS Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg77-Gly374, with an N-terminal His tag. Predicted molecular weight: 34.99 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Receptor-type tyrosine-protein phosphatase S (PTPRS) is a ~217 kDa protein. Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan. For research use only.
Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth. Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for normal brain development, especially for normal development of the pituitary gland and the olfactory bulb.
| Product Name: | Human PTPRS Recombinant Protein (N-His) |
| SKU: | GXRP02189 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | R-PTP-S, PTPRS, Receptor-type tyrosine-protein phosphatase S, R-PTP-sigma, Receptor-type tyrosine-protein phosphatase sigma |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg77-Gly374 |
| Calculated MW: | 34.99 kDa |
| UniProt: | Q13332 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |