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Human RAB8B Recombinant Protein (N-His)
Key Features

Human RAB8B Recombinant Protein (N-His) (GXRP04441)

SKU GXRP04441
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human RAB8B Recombinant Protein (N-His)

Human RAB8B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ala185, with an N-terminal His tag. Predicted molecular weight: 23.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ras-related protein Rab-8B (RAB8B) is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. For research use only.

Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB8B may be involved in polarized vesicular trafficking and neurotransmitter release (Probable). May participate in cell junction dynamics in Sertoli cells. May also participate in the export of a subset of neosynthesized proteins through a Rab8-Rab10-Rab11-dependent endososomal export route.

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