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Human RAD51 Recombinant Protein (N-His)
Key Features

Human RAD51 Recombinant Protein (N-His) (GXRP02073)

SKU GXRP02073
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human RAD51 Recombinant Protein (N-His)

Human RAD51 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val174-Asp339, with an N-terminal His tag. Predicted molecular weight: 20.4 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA repair protein RAD51 homolog 1 is a ~36 kDa protein. Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). For research use only.

Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR.

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