Description
Human RB1CC1 Recombinant Protein (N-His)
Human RB1CC1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu1447-Val1594, with an N-terminal His tag. Predicted molecular weight: 19.48 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. RB1-inducible coiled-coil protein 1 (RB1CC1) is a ~183 kDa protein. Involved in autophagy. For research use only.
Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy. Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis. Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways.
| Product Name: | Human RB1CC1 Recombinant Protein (N-His) |
| SKU: | GXRP04091 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | FAK family kinase-interacting protein of 200 kDa, RB1CC1, FIP200, RBICC, RB1-inducible coiled-coil protein 1, KIAA0203 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu1447-Val1594 |
| Calculated MW: | 19.48 kDa |
| UniProt: | Q8TDY2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
