Description
Human RBBP7 Recombinant Protein (N-His)
Human RBBP7 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile120-Ser425, with an N-terminal His tag. Predicted molecular weight: 36.48 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Histone-binding protein RBBP7 is a ~47 kDa protein. Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. For research use only.
Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
| Product Name: | Human RBBP7 Recombinant Protein (N-His) |
| SKU: | GXRP04673 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Nucleosome-remodeling factor subunit RBAP46, Histone-binding protein RBBP7, RBAP46, Retinoblastoma-binding protein 7, Histone acetyltransferase type B subunit 2, Retinoblastoma-binding protein p46, RBBP-7, RBBP7 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile120-Ser425 |
| Calculated MW: | 36.48 kDa |
| UniProt: | Q16576 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
