Description
Human RBL2 Recombinant Protein (N-His)
Human RBL2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu448-Pro624, with an N-terminal His tag. Predicted molecular weight: 23.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Retinoblastoma-like protein 2 is a ~128 kDa protein. Key regulator of entry into cell division. For research use only.
Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters.
| Product Name: | Human RBL2 Recombinant Protein (N-His) |
| SKU: | GXRP11097 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 130 kDa retinoblastoma-associated protein, RB2, RBL2, RBR-2, Retinoblastoma-like protein 2, Retinoblastoma-related protein 2, p130, pRb2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu448-Pro624 |
| Calculated MW: | 23.20 kDa |
| UniProt: | Q08999 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
