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Human RCCD1 Recombinant Protein (N-His)
Key Features

Human RCCD1 Recombinant Protein (N-His) (GXRP07693)

SKU GXRP07693
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human RCCD1 Recombinant Protein (N-His)

Human RCCD1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ser376, with an N-terminal His tag. Predicted molecular weight: 42.24 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. RCC1 domain-containing protein 1 (RCCD1) is a ~40 kDa protein. Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. For research use only.

Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.

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