Description
Human RCVRN Recombinant Protein (N-His)
Human RCVRN Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly2-Ala200, with an N-terminal His tag. Predicted molecular weight: 25.29 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Recoverin (RCVRN) is a ~23 kDa protein. Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells. For research use only.
Modulates light sensitivity of cone photoreceptor in dark and dim conditions. In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin. Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells. Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light.
| Product Name: | Human RCVRN Recombinant Protein (N-His) |
| SKU: | GXRP01478 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | RCVRN, Recoverin, RCV1, Cancer-associated retinopathy protein, Protein CAR |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly2-Ala200 |
| Calculated MW: | 25.29 kDa |
| UniProt: | P35243 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |