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Human RECQL5 Recombinant Protein (N-His)
Key Features

Human RECQL5 Recombinant Protein (N-His) (GXRP07447)

SKU GXRP07447
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human RECQL5 Recombinant Protein (N-His)

Human RECQL5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp11-Thr218, with an N-terminal His tag. Predicted molecular weight: 25.26 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ATP-dependent DNA helicase Q5 (RECQL5) is a ~108 kDa protein. DNA helicase that plays an important role in DNA replication, transcription and repair. For research use only.

Probably unwinds DNA in a 3'-5' direction (Probable). Binds to the RNA polymerase II subunit POLR2A during transcription elongation and suppresses transcription-associated genomic instability. Also associates with POLR1A and enforces the stability of ribosomal DNA arrays. Plays an important role in mitotic chromosome separation after cross-over events and cell cycle progress.

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