Human ROR1 (ABL202) Antibody (ADC, Payload-Free) is a research-grade biosimilar monoclonal antibody targeting Neurotrophic tyrosine kinase. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Supplied as the antibody component without the cytotoxic payload. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling.
Product Name:
Human ROR1 (ABL202) Antibody (ADC, Payload-Free)
SKU:
GXBS01826
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Clone:
ABL202
Target:
Neurotrophic tyrosine kinase
Isotype:
IgG
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
ABL202
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
