Description
Human RRM2B Recombinant Protein (N-His)
Human RRM2B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Phe351, with an N-terminal His tag. Predicted molecular weight: 42.9 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) is a ~40 kDa protein. Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. For research use only.
Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
| Product Name: | Human RRM2B Recombinant Protein (N-His) |
| SKU: | GXRP02497 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | p53R2, p53-inducible ribonucleotide reductase small subunit 2-like protein, P53R2, RRM2B, TP53-inducible ribonucleotide reductase M2 B, Ribonucleoside-diphosphate reductase subunit M2 B |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Phe351 |
| Calculated MW: | 42.9 kDa |
| UniProt: | Q7LG56 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
