Description
Human RYR2 Recombinant Protein (N-His)
Human RYR2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg606, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ryanodine receptor 2 is a ~564 kDa protein. Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytosol and thereby plays a key role in triggering cardiac muscle contraction. For research use only.
Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) cytosolic levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis.
| Product Name: | Human RYR2 Recombinant Protein (N-His) |
| SKU: | GXRP13837 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, RYR-2, RYR2, RyR2, Ryanodine receptor 2, Type 2 ryanodine receptor, hRYR-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg606 |
| UniProt: | Q92736 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
