Description
Human SASH1 Recombinant Protein (N-His)
Human SASH1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val1091-Met1247, with an N-terminal His tag. Predicted molecular weight: 19.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. SAM and SH3 domain-containing protein 1 (SASH1) is a ~136 kDa protein. Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. For research use only.
It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation. Regulates TRAF6 and MAP3K7 ubiquitination. Involved in the regulation of cell mobility. Regulates lipolysaccharide (LPS)-induced endothelial cell migration.
| Product Name: | Human SASH1 Recombinant Protein (N-His) |
| SKU: | GXRP07449 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | SAM and SH3 domain-containing protein 1, Proline-glutamate repeat-containing protein, SASH1, KIAA0790, PEPE1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val1091-Met1247 |
| Calculated MW: | 19.54 kDa |
| UniProt: | O94885 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
