Description
Human SATB2 Recombinant Protein (N-His)
Human SATB2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly57-Lys231, with an N-terminal His tag. Predicted molecular weight: 22.01 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA-binding protein SATB2 is a ~82 kDa protein. Binds to DNA, at nuclear matrix- or scaffold-associated regions. For research use only.
Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression.
| Product Name: | Human SATB2 Recombinant Protein (N-His) |
| SKU: | GXRP04574 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | SATB2, DNA-binding protein SATB2, KIAA1034, Special AT-rich sequence-binding protein 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly57-Lys231 |
| Calculated MW: | 22.01 kDa |
| UniProt: | Q9UPW6 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
