Description
Human SCNN1B Recombinant Protein (N-His)
Human SCNN1B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser76-Ala512, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Epithelial sodium channel subunit beta is a ~72 kDa protein. This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. For research use only.
ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance.
| Product Name: | Human SCNN1B Recombinant Protein (N-His) |
| SKU: | GXRP13856 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Amiloride-sensitive sodium channel subunit beta, Beta-ENaC, Beta-NaCH, ENaC subunit beta, ENaCB, Epithelial Na(+) channel subunit beta, Epithelial sodium channel subunit beta, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser76-Ala512 |
| UniProt: | P51168 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
