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Human SDCCAG8 Recombinant Protein (N-His)
Key Features

Human SDCCAG8 Recombinant Protein (N-His) (GXRP07684)

SKU GXRP07684
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SDCCAG8 Recombinant Protein (N-His)

Human SDCCAG8 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu348-Leu680, with an N-terminal His tag. Predicted molecular weight: 41.76 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Serologically defined colon cancer antigen 8 (SDCCAG8) is a ~82 kDa protein. Plays a role in the establishment of cell polarity and epithelial lumen formation. For research use only.

Also plays an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.

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