Description
Human SEPTIN4 Recombinant Protein (N-His)
Human SEPTIN4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly142-Met392, with an N-terminal His tag. Predicted molecular weight: 31.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Septin-4 (SEPTIN4) is a ~112 kDa protein. Filament-forming cytoskeletal GTPase (Probable). For research use only.
Pro-apoptotic protein involved in LGR5-positive intestinal stem cell and Paneth cell expansion in the intestines, via its interaction with XIAP. May also play a role in the regulation of cell fate in the intestine. Positive regulator of apoptosis involved in hematopoietic stem cell homeostasis; via its interaction with XIAP. Negative regulator of repair and hair follicle regeneration in response to injury, due to inhibition of hair follicle stem cell proliferation, potentially via its interaction with XIAP.
| Product Name: | Human SEPTIN4 Recombinant Protein (N-His) |
| SKU: | GXRP07343 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Septin-4, Bradeion beta, Brain protein H5, CE5B3 beta, Cell division control-related protein 2, hCDCREL-2, Peanut-like protein 2, SEPTIN4, C17orf47, PNUTL2, SEP4, SEPT4, hucep-7 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly142-Met392 |
| Calculated MW: | 31.17 kDa |
| UniProt: | O43236 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |