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Human SEPTIN4 Recombinant Protein (N-His)
Key Features

Human SEPTIN4 Recombinant Protein (N-His) (GXRP07343)

SKU GXRP07343
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SEPTIN4 Recombinant Protein (N-His)

Human SEPTIN4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly142-Met392, with an N-terminal His tag. Predicted molecular weight: 31.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Septin-4 (SEPTIN4) is a ~112 kDa protein. Filament-forming cytoskeletal GTPase (Probable). For research use only.

Pro-apoptotic protein involved in LGR5-positive intestinal stem cell and Paneth cell expansion in the intestines, via its interaction with XIAP. May also play a role in the regulation of cell fate in the intestine. Positive regulator of apoptosis involved in hematopoietic stem cell homeostasis; via its interaction with XIAP. Negative regulator of repair and hair follicle regeneration in response to injury, due to inhibition of hair follicle stem cell proliferation, potentially via its interaction with XIAP.

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