Description
Human SERPINB1 Recombinant Protein (N-His)
Human SERPINB1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu13-Leu252, with an N-terminal His tag. Predicted molecular weight: 29.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Leukocyte elastase inhibitor (SERPINB1) is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. For research use only.
Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of GZMH by directly blocking its proteolytic activity.
| Product Name: | Human SERPINB1 Recombinant Protein (N-His) |
| SKU: | GXRP01406 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ELANH2, Peptidase inhibitor 2, Serpin B1, SERPINB1, MNEI, M/NEI, EI, LEI, PI2, Monocyte/neutrophil elastase inhibitor, PI-2, Leukocyte elastase inhibitor |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu13-Leu252 |
| Calculated MW: | 29.54 kDa |
| UniProt: | P30740 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
