Description
Human SGPL1 Recombinant Protein (N-His)
Human SGPL1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser122-Tyr550, with an N-terminal His tag. Predicted molecular weight: 49.64 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sphingosine-1-phosphate lyase 1 is a ~63 kDa protein. Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. For research use only.
Elevates stress-induced ceramide production and apoptosis. Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP.
| Product Name: | Human SGPL1 Recombinant Protein (N-His) |
| SKU: | GXRP11841 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:4.1.2.27, KIAA1252, S1PL, SGPL1, SP-lyase 1, SPL 1, Sphingosine-1-phosphate aldolase, Sphingosine-1-phosphate lyase 1, hSPL |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser122-Tyr550 |
| Calculated MW: | 49.64 kDa |
| UniProt: | O95470 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
