Description
Human SGPP1 Recombinant Protein (N-His)
Human SGPP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu131, with an N-terminal His tag. Predicted molecular weight: 16.15 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sphingosine-1-phosphate phosphatase 1 (SGPP1) is a ~49 kDa protein. Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P. For research use only.
Does not act on ceramide 1-phosphate, lysophosphatidic acid or phosphatidic acid. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. Regulates the intracellular levels of the bioactive sphingolipid metabolite S1P that regulates diverse biological processes acting both as an extracellular receptor ligand or as an intracellular second messenger. Involved in efficient ceramide synthesis from exogenous sphingoid bases.
| Product Name: | Human SGPP1 Recombinant Protein (N-His) |
| SKU: | GXRP02815 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Sphingosine-1-phosphatase 1, SPPase1, SPP-1, hSPP1, Sphingosine-1-phosphate phosphatase 1, hSPPase1, Spp1, SPP1, SGPP1, Sphingosine-1-phosphate phosphohydrolase 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu131 |
| Calculated MW: | 16.15 kDa |
| UniProt: | Q9BX95 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |