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Human SGPP1 Recombinant Protein (N-His)
Key Features

Human SGPP1 Recombinant Protein (N-His) (GXRP02815)

SKU GXRP02815
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SGPP1 Recombinant Protein (N-His)

Human SGPP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu131, with an N-terminal His tag. Predicted molecular weight: 16.15 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sphingosine-1-phosphate phosphatase 1 (SGPP1) is a ~49 kDa protein. Specifically dephosphorylates sphingosine 1-phosphate (S1P), dihydro-S1P, and phyto-S1P. For research use only.

Does not act on ceramide 1-phosphate, lysophosphatidic acid or phosphatidic acid. Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. Regulates the intracellular levels of the bioactive sphingolipid metabolite S1P that regulates diverse biological processes acting both as an extracellular receptor ligand or as an intracellular second messenger. Involved in efficient ceramide synthesis from exogenous sphingoid bases.

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