Description
Human SH3PXD2A Recombinant Protein (N-His)
Human SH3PXD2A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asn129, with an N-terminal His tag. Predicted molecular weight: 17.51 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. SH3 and PX domain-containing protein 2A (SH3PXD2A) is a ~125 kDa protein. Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. For research use only.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
| Product Name: | Human SH3PXD2A Recombinant Protein (N-His) |
| SKU: | GXRP04445 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA0418, Tyrosine kinase substrate with five SH3 domains, TKS5, SH3 multiple domains protein 1, SH3PXD2A, SH3MD1, SH3 and PX domain-containing protein 2A, Five SH3 domain-containing protein, Adapter protein TKS5, FISH |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asn129 |
| Calculated MW: | 17.51 kDa |
| UniProt: | Q5TCZ1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
