Description
Human SHPRH Recombinant Protein (N-His)
Human SHPRH Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu1381-Glu1683, with an N-terminal His tag. Predicted molecular weight: 36.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase SHPRH is a ~193 kDa protein. E3 ubiquitin-protein ligase involved in DNA repair. For research use only.
Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
| Product Name: | Human SHPRH Recombinant Protein (N-His) |
| SKU: | GXRP09700 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | E3 ubiquitin-protein ligase SHPRH; 2.3.2.27; 3.6.4.-; RING-type E3 ubiquitin transferase SHPRH; SNF2, histone-linker, PHD and RING finger domain-containing helicase; SHPRH; KIAA2023 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu1381-Glu1683 |
| Calculated MW: | 36.12 kDa |
| UniProt: | Q149N8 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
