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Human SLC17A5 Recombinant Protein (N-His)
Key Features

Human SLC17A5 Recombinant Protein (N-His) (GXRP03216)

SKU GXRP03216
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SLC17A5 Recombinant Protein (N-His)

Human SLC17A5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr146-Phe405, with an N-terminal His tag. Predicted molecular weight: 31.44 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sialin (SLC17A5) is a ~54 kDa protein. Multifunctional anion transporter that operates via two distinct transport mechanisms, namely proton-coupled anion cotransport and membrane potential-dependent anion transport. For research use only.

Electroneutral proton-coupled acidic monosaccharide symporter, with a sugar to proton stoichiometry of 1:1. Exports glucuronic acid and free sialic acid derived from sialoglycoconjugate degradation out of lysosomes, driven by outwardly directed lysosomal pH gradient. May regulate lysosome function and metabolism of sialylated conjugates that impact oligodendrocyte lineage differentiation and myelinogenesis in the central nervous system. Electrogenic proton-coupled nitrate symporter that transports nitrate ions across the basolateral membrane of salivary gland acinar cells, with nitrate to proton stoichiometry of 2:1.

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