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Human SLC5A1 Recombinant Protein (N-His)
Key Features

Human SLC5A1 Recombinant Protein (N-His) (GXRP10592)

SKU GXRP10592
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human SLC5A1 Recombinant Protein (N-His)

Human SLC5A1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp230-Pro277&Ser335-Gly380&Arg564-Thr643, with an N-terminal His tag. Predicted molecular weight: 22.70 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Sodium/glucose cotransporter 1 is a ~73 kDa protein. Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. For research use only.

Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis.

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