Description
Human SLCO1A2 Recombinant Protein (N-His)
Human SLCO1A2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe406-Phe513, with an N-terminal His tag. Predicted molecular weight: 13.78 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Solute carrier organic anion transporter family member 1A2 (SLCO1A2) is a ~74 kDa protein. Na(+)-independent transporter that mediates the cellular uptake of a broad range of organic anions such as the endogenous bile salts cholate and deoxycholate, either in their unconjugated or conjugated forms (taurocholate and glycocholate), at the plasmam membrane. For research use only.
Responsible for intestinal absorption of bile acids. Transports dehydroepiandrosterone 3-sulfate (DHEAS), a major circulating steroid secreted by the adrenal cortex, as well as estrone 3-sulfate and 17beta-estradiol 17-O-(beta-D-glucuronate). Mediates apical uptake of all-trans-retinol (atROL) across human retinal pigment epithelium, which is essential to maintaining the integrity of the visual cycle and thus vision. Involved in the uptake of clinically used drugs.
| Product Name: | Human SLCO1A2 Recombinant Protein (N-His) |
| SKU: | GXRP01639 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | OATP, OATP1, SLC21A3, OATP-A, Solute carrier family 21 member 3, Solute carrier organic anion transporter family member 1A2, OATP-1, Sodium-independent organic anion transporter, OATP1A2, Organic anion-transporting polypeptide 1, SLCO1A2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe406-Phe513 |
| Calculated MW: | 13.78 kDa |
| UniProt: | P46721 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
