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Human SLU7 Recombinant Protein (N-His)
Key Features

Human SLU7 Recombinant Protein (N-His) (GXRP07464)

SKU GXRP07464
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human SLU7 Recombinant Protein (N-His)

Human SLU7 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met28-Tyr173, with an N-terminal His tag. Predicted molecular weight: 19.37 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Pre-mRNA-splicing factor SLU7 is a ~68 kDa protein. Required for pre-mRNA splicing as component of the spliceosome. For research use only.

Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.

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