Description
Human SMARCA5 Recombinant Protein (N-His)
Human SMARCA5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr166-Gln634, with an N-terminal His tag. Predicted molecular weight: 57.10 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a ~121 kDa protein. ATPase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. For research use only.
Catalytic subunit of ISWI chromatin-remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair; this may require intact histone H4 tails. Within the ISWI chromatin-remodeling complexes, slides edge- and center-positioned histone octamers away from their original location on the DNA template. Catalytic activity and histone octamer sliding propensity is regulated and determined by components of the ISWI chromatin-remodeling complexes. The BAZ1A/ACF1-, BAZ1B/WSTF-, BAZ2A/TIP5- and BAZ2B-containing ISWI chromatin-remodeling complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template in an ATP-dependent manner.
| Product Name: | Human SMARCA5 Recombinant Protein (N-His) |
| SKU: | GXRP10962 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:3.6.4.-, SMARCA5, SNF2H, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, Sucrose nonfermenting protein 2 homolog, WCRF135, hSNF2H |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr166-Gln634 |
| Calculated MW: | 57.10 kDa |
| UniProt: | O60264 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
