Description
Human SMC3 Recombinant Protein (N-His)
Human SMC3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu995-Glu1181, with an N-terminal His tag. Predicted molecular weight: 23.15 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Structural maintenance of chromosomes protein 3 (SMC3) is a ~141 kDa protein. Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. For research use only.
The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
| Product Name: | Human SMC3 Recombinant Protein (N-His) |
| SKU: | GXRP03091 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BMH, CSPG6, SMC protein 3, Basement membrane-associated chondroitin proteoglycan, SMC3, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, BAM, hCAP, Bamacan, Structural maintenance of chromosomes protein 3, SMC3L1, SMC-3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu995-Glu1181 |
| Calculated MW: | 23.15 kDa |
| UniProt: | Q9UQE7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
